Episode 244: P.D. Mangan

by Brian Lenzkes, MD | Mar 26, 2025 | Podcast | 0 comments

View Episode 244: P.D. Mangan on YouTube
View Episode 244: P.D. Mangan on Rumble
Listen to Episode 244: P.D. Mangan on iTunes
Listen to Episode 244: P.D. Mangan on Spotify
Learn how to support the Life’s Best Medicine Podcast on Patreon

Thank you for tuning in for another episode of Life’s Best Medicine. P.D. Mangan is is a 68-year-old scientist with expertise in microbiology, biochemistry, and pharmacology. Passionate about the impact of diet and exercise on anti-aging and longevity, he champions metabolic health, the value of real foods, and the importance of resistance training.

In this episode, Dr. Brian and P.D. talk about…

(00:00) Intro
(05:13) Chronic fatigue, sleep, and how to crush fatigue for good
(16:11) Exercise, fatigue, and health
(21:28) How to work work effectively and efficiently
(26:58) Acute versus chronic stress
(29:38) Carb loading
(33:45) Why running too much can be unhealthy for your heart
(36:58) How P.D. Mangan would start with a coaching client who has been relatively sedentary for a long time
(42:57) Strength training, losing body fat, and insulin resistance
(47:51) Strength training, being sedentary, and acute pain
(51:09) Some observations that have surprised P.D. over the course of his coaching career
(53:40) Alcohol, exercise, and carbs
(58:14) Advice and inspiration for getting started with your health journey
(01:06:21) Outro and plugs