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Episode 316: Don Moxley – HRV, Exercise, and Longevity

by | Oct 29, 2026 | Podcast | 0 comments


View Episode 316: Don Moxley – HRV, Exercise, and Longevity on YouTube
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Don Moxley is an exercise physiologist, human performance expert, and researcher focused on the science of aging, recovery, and longevity. With a background in exercise science and performance optimization, he explores how movement, strength training, and lifestyle strategies can improve health and help people perform at their best throughout life.

He has also served as the first paid sport scientist for The Ohio State University wrestling program and has helped elite athletes achieve championship-level results. His current work explores heart rate variability (HRV), cellular renewal, and the science of healthy aging, making complex research accessible and actionable.

Timestamps:

  • (00:00) Intro
  • (06:14) How Don’s became interested in exercise science
  • (10:08) How Don first became interested in HRV and how it impacts athletic performance
  • (19:06) The impacts of poor sleep and alcohol on athletic performance
  • (28:26) CGMs and health data
  • (34:14) Hyperbaric therapy and HRV
  • (37:13) Other therapies that improve stress and HRV
  • (41:11) Adverse Childhood Events and athletics
  • (46:19) HRV+
  • (53:00) Environmental health, cold plunge, and sauna
  • (54:42) The best kind of exercise for HRV and how to factor in bio individuality
  • (58:28) Cortisol
  • (01:01:01) Psychedelics and trauma
  • (01:03:07) Cancer and HRV
  • (01:08:13) Fitness, health, and purpose
  • (01:12:08) Outro

For more information, please see the links below. Thank you for listening!

The Life’s Best Medicine Podcast is sponsored by HLTH Code.

LINKS:

Don Moxley:

Dr. Brian Lenzkes:

HLTH Code: